Activating Compound | Comment | Organism | Structure |
---|---|---|---|
proteoglycan | there is evidence indicating that the processing of pro-MC-CPA into active protease is dependent on proteoglycan | Mus musculus | |
proteoglycan | there is evidence indicating that the processing of pro-MC-CPA into active protease is dependent on proteoglycan | Homo sapiens | |
proteoglycan | there is evidence indicating that the processing of pro-MC-CPA into active protease is dependent on proteoglycan | Rattus norvegicus |
Application | Comment | Organism |
---|---|---|
medicine | mast cell-proteases are considered as promising drug targets | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
latexin | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
secretory granule | - |
Mus musculus | 30141 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | cleavage of the signal peptide and subsequent cleavage of the propeptide results in the formation of the mature enzyme | Mus musculus |
proteolytic modification | cleavage of the signal peptide and subsequent cleavage of the propeptide results in the formation of the mature enzyme | Homo sapiens |
proteolytic modification | cleavage of the signal peptide and subsequent cleavage of the propeptide results in the formation of the mature enzyme | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestinal mucosa | - |
Mus musculus | - |
intestinal mucosa | - |
Homo sapiens | - |
mast cell | - |
Mus musculus | - |
mast cell | - |
Homo sapiens | - |
mast cell | - |
Rattus norvegicus | - |
peritoneum | - |
Mus musculus | - |
secretion | - |
Homo sapiens | - |
skin | - |
Mus musculus | - |
skin | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | shown in an ex vivo system of peritoneal exudates cells | Mus musculus | angiotensin II + His-Leu | - |
? | |
angiotensin I + H2O | shown in an ex vivo system of peritoneal exudates cells | Homo sapiens | angiotensin II + His-Leu | - |
? | |
angiotensin I + H2O | shown in an ex vivo system of peritoneal exudates cells | Rattus norvegicus | angiotensin II + His-Leu | - |
? | |
angiotensin I + H2O | - |
Mus musculus | des-Leu10 angiotensin I + Leu | - |
? | |
angiotensin I + H2O | - |
Homo sapiens | des-Leu10 angiotensin I + Leu | - |
? | |
angiotensin I + H2O | - |
Rattus norvegicus | des-Leu10 angiotensin I + Leu | - |
? | |
apoB-100 + H2O | - |
Mus musculus | ? | - |
? | |
apoB-100 + H2O | - |
Homo sapiens | ? | - |
? | |
apoB-100 + H2O | - |
Rattus norvegicus | ? | - |
? | |
ET-1 + H2O | - |
Mus musculus | ? | - |
? | |
ET-1 + H2O | - |
Homo sapiens | ? | - |
? | |
ET-1 + H2O | - |
Rattus norvegicus | ? | - |
? | |
Leu5-enkephalin + H2O | - |
Mus musculus | ? | - |
? | |
Leu5-enkephalin + H2O | - |
Homo sapiens | ? | - |
? | |
Leu5-enkephalin + H2O | - |
Rattus norvegicus | ? | - |
? | |
neurotensin + H2O | - |
Mus musculus | ? | - |
? | |
neurotensin + H2O | - |
Homo sapiens | ? | - |
? | |
neurotensin + H2O | - |
Rattus norvegicus | ? | - |
? | |
sarafotoxin + H2O | - |
Mus musculus | ? | - |
? | |
sarafotoxin + H2O | - |
Homo sapiens | ? | - |
? | |
sarafotoxin + H2O | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carboxypeptidase a | - |
Mus musculus |
carboxypeptidase a | - |
Homo sapiens |
carboxypeptidase a | - |
Rattus norvegicus |
CPA | - |
Mus musculus |
CPA | - |
Homo sapiens |
CPA | - |
Rattus norvegicus |
MC-CPA | - |
Mus musculus |
MC-CPA | - |
Homo sapiens |
MC-CPA | - |
Rattus norvegicus |